viernes
10:30 - 12:00 SUM
Simposio SUM: Conferencia Inaugural SUM
Palabras a cargo de la directiva.
Genomic features of toxin producing cyanobacteria, the case of Cylindrospermopsis raciborskii
Conferencista
Mónica Vásquez - Universidad de Chile (Chile)
Coordinadora
Claudia Piccini - Departamento de Microbiología, IIBCE (Uruguay)
| Conferencista invitado
Genomic features of toxin producing cyanobacteria, the case of Cylindrospermopsis raciborskii (#0103)
Mónica Vásquez 1
1 - Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, P. Universidad Católica de Chile..
Resumen:
Cyanobacterial bloom-forming species are a persistent global problem where Cylindrospermopsis raciborskii, has been described as invader species that cause serious problems because of the wide variety of toxic compounds that it produces. Toxic metabolites can be associated with dermal rash, neural disturbance, hepatic and digestive disorder among others. This species has been characterized as a producer of saxitoxin (STX), cylindrospermopsin (CYL), and recently hassallidin (HAS). In order to understand the mechanisms responsible for the synthesis of these toxins and metabolites, representative strains of this species have been characterized both genetically and chromatographically. To provide further data to better understand the genomics and physiology of C. raciborskii, including its high capacity for dispersal, we performed a genome sequence analysis of Australian strain CS-508 and Uruguayan strain MVCC14, including gene annotation using the Clusters of Orthologous Group (COG) database. We conducted a comparative genome analysis on five Australian C. raciborskii strains (CS-505, CS-506, CS-508, CS-509) and the Uruguayan strain MVCC14, in addition to R. brookii D9 (from Brazil) to identify common genes. Interesting features and its implications were deeply and carefully analyzed.
Contacto: mvasquez@bio.puc.cl
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Cyanobacterial bloom-forming species are a persistent global problem where Cylindrospermopsis raciborskii, has been described as invader species that cause serious problems because of the wide variety of toxic compounds that it produces. Toxic metabolites can be associated with dermal rash, neural disturbance, hepatic and digestive disorder among others. This species has been characterized as a producer of saxitoxin (STX), cylindrospermopsin (CYL), and recently hassallidin (HAS). In order to understand the mechanisms responsible for the synthesis of these toxins and metabolites, representative strains of this species have been characterized both genetically and chromatographically. To provide further data to better understand the genomics and physiology of C. raciborskii, including its high capacity for dispersal, we performed a genome sequence analysis of Australian strain CS-508 and Uruguayan strain MVCC14, including gene annotation using the Clusters of Orthologous Group (COG) database. We conducted a comparative genome analysis on five Australian C. raciborskii strains (CS-505, CS-506, CS-508, CS-509) and the Uruguayan strain MVCC14, in addition to R. brookii D9 (from Brazil) to identify common genes. Interesting features and its implications were deeply and carefully analyzed.
Contacto: mvasquez@bio.puc.cl
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